EC number:2.3.1.263
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.263 |
|---|---|
| Description: | 2-amino-4-oxopentanoate thiolase. |
| Alternative Name: |
AKP thiolase. 2-amino-4-ketopentanoate thiolase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.263 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.263 |
| KEGG Enzyme Link: | KEGG2.3.1.263 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.263 |
| ExPASy Enzyme Link: | ExPASy2.3.1.263 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.263 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.263 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.263 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.263 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.263 |
EC number:2.3.1.263
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:51436 | acetyl-CoA + D-alanine = (2R)-2-amino-4-oxopentanoate + CoA |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Ornithine degradation in Clostridium sticklandii; pyridoxal phosphate and coenzyme A dependent thiolytic cleavage of 2-amino-4-ketopentanoate to alanine and acetyl coenzyme A. | Jeng IM, Somack R, Barker HA | 1974 Jul 2 | 4407783 |
| A conserved gene cluster rules anaerobic oxidative degradation of L-ornithine. | Fonknechten N, Perret A, Perchat N, Tricot S, Lechaplais C, Vallenet D, Vergne C, Zaparucha A, Le Paslier D, Weissenbach J, Salanoubat M | 2009 May | 19251850 |