EC number:2.3.1.265
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.265 |
|---|---|
| Description: | Phosphatidylinositol dimannoside acyltransferase. |
| Alternative Name: |
PIM2 acyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.265 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.265 |
| KEGG Enzyme Link: | KEGG2.3.1.265 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.265 |
| ExPASy Enzyme Link: | ExPASy2.3.1.265 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.265 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.265 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.265 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.265 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.265 |
EC number:2.3.1.265
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:52436 | a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + an acyl-CoA = 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + CoA |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[SH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of the acyltransferase involved in biosynthesis of the major mycobacterial cell envelope glycolipid--monoacylated phosphatidylinositol dimannoside. | Svetlíková Z, Baráth P, Jackson M, Korduláková J, Mikušová K | 2014 Aug | 24810911 |
| Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species. | Korduláková J, Gilleron M, Puzo G, Brennan PJ, Gicquel B, Mikusová K, Jackson M | 2003 Sep 19 | 12851411 |
| RHEA:47412 | 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1->2)-D-myo-inositol] + an acyl-CoA = 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1->2)-D-myo-inositol] + CoA |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[SH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of the acyltransferase involved in biosynthesis of the major mycobacterial cell envelope glycolipid--monoacylated phosphatidylinositol dimannoside. | Svetlíková Z, Baráth P, Jackson M, Korduláková J, Mikušová K | 2014 Aug | 24810911 |
| Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species. | Korduláková J, Gilleron M, Puzo G, Brennan PJ, Gicquel B, Mikusová K, Jackson M | 2003 Sep 19 | 12851411 |