EC number:2.3.1.271
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.271 |
|---|---|
| Description: | L-glutamate-5-semialdehyde N-acetyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.271 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.271 |
| KEGG Enzyme Link: | KEGG2.3.1.271 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.271 |
| ExPASy Enzyme Link: | ExPASy2.3.1.271 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.271 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.271 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.271 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.271 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.271 |
EC number:2.3.1.271
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:48232 | acetyl-CoA + L-glutamate 5-semialdehyde = CoA + H(+) + N-acetyl-L-glutamate 5-semialdehyde |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism. | Nasuno R, Hirano Y, Itoh T, Hakoshima T, Hibi T, Takagi H | 2013 Jul 16 | 23818613 |
| The proline metabolism intermediate Δ1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast. | Nishimura A, Nasuno R, Takagi H | 2012 Jul 30 | 22698729 |
| An antioxidative mechanism mediated by the yeast N-acetyltransferase Mpr1: oxidative stress-induced arginine synthesis and its physiological role. | Nishimura A, Kotani T, Sasano Y, Takagi H | 2010 Sep | 20550582 |
| Role of the yeast acetyltransferase Mpr1 in oxidative stress: regulation of oxygen reactive species caused by a toxic proline catabolism intermediate. | Nomura M, Takagi H | 2004 Aug 24 | 15308773 |
| A novel acetyltransferase found in Saccharomyces cerevisiae Sigma1278b that detoxifies a proline analogue, azetidine-2-carboxylic acid. | Shichiri M, Hoshikawa C, Nakamori S, Takagi H | 2001 Nov 9 | 11555637 |