EC number:2.3.1.28

Enzyme

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EC Tree
     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.28
Description:Chloramphenicol O-acetyltransferase.
Prosite: PDOC00094; PDOC00093;
PDB:
PDBScop
3U9F 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085;
1Q23 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085;
1PD5 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085;
3U9B 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085; 8069084; 8069085;
4CLA 8031958; 8044336;
 » show all
Cath: 3.30.559.10; 2.160.10.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.28
BRENDA Enzyme Link: BRENDA 2.3.1.28
KEGG Enzyme Link: KEGG2.3.1.28
BioCyc Enzyme Link: BioCyc 2.3.1.28
ExPASy Enzyme Link: ExPASy2.3.1.28
EC2PDB Enzyme Link: EC2PDB 2.3.1.28
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.28
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.28
IntEnz Enzyme Link: IntEnz 2.3.1.28
MEDLINE Enzyme Link: MEDLINE 2.3.1.28

EC number:2.3.1.28

MSA:

2.3.1.28;
Phylogenetic Tree:

2.3.1.28;
Uniprot:
M-CSA:
RHEA:18421 acetyl-CoA + chloramphenicol = chloramphenicol 3-acetate + CoA
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Structure of the hexapeptide xenobiotic acetyltransferase from Pseudomonas aeruginosa.Beaman TW, Sugantino M, Roderick SL1998 May 129578552