EC number:2.3.1.29

Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.29
Description:Glycine C-acetyltransferase.
Alternative Name: 2-amino-3-ketobutyrate coenzyme A ligase.
Prosite: PDOC00518;
PDB:
PDBScop
2F8J 8028282; 8040661; 8028282; 8040661; 8028282; 8040661; 8028282; 8040661;
1UU1 8028282; 8040661; 8028282; 8040661; 8028282; 8040661; 8028282; 8040661;
1UU0 8028282; 8040661; 8028282; 8040661; 8028282; 8040661; 8028282; 8040661;
1H1C 8028282; 8040661; 8028282; 8040661; 8028282; 8040661; 8028282; 8040661;
2BWP 8026406; 8038785; 8026406; 8038785; 8026406; 8038785; 8026406; 8038785;
 » show all
Cath: 3.40.50.720; 3.40.640.10; 3.90.1150.10; 3.90.180.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.29
BRENDA Enzyme Link: BRENDA 2.3.1.29
KEGG Enzyme Link: KEGG2.3.1.29
BioCyc Enzyme Link: BioCyc 2.3.1.29
ExPASy Enzyme Link: ExPASy2.3.1.29
EC2PDB Enzyme Link: EC2PDB 2.3.1.29
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.29
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.29
IntEnz Enzyme Link: IntEnz 2.3.1.29
MEDLINE Enzyme Link: MEDLINE 2.3.1.29

EC number:2.3.1.29

MSA:

2.3.1.29;
Phylogenetic Tree:

2.3.1.29;
Uniprot:
M-CSA:
RHEA:20736 acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]=[C;H0;+0:5](-[*:6])-[S;H0;+0:7]-[*:8]>>[*:8]-[SH;+0:7].[*:4]=[C;H0;+0:5](-[*:6])-[CH;+0:2](-[*:1])-[*:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.Schmidt A, Sivaraman J, Li Y, Larocque R, Barbosa JA, Smith C, Matte A, Schrag JD, Cygler M2001 May 111318637