Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.1 Transferring groups other than aminoacyl groups
ID:2.3.1.45
Description:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.1.45
BRENDA Enzyme Link: BRENDA 2.3.1.45
KEGG Enzyme Link: KEGG2.3.1.45
BioCyc Enzyme Link: BioCyc 2.3.1.45
ExPASy Enzyme Link: ExPASy2.3.1.45
EC2PDB Enzyme Link: EC2PDB 2.3.1.45
ExplorEnz Enzyme Link: ExplorEnz 2.3.1.45
PRIAM enzyme-specific profiles Link: PRIAM 2.3.1.45
IntEnz Enzyme Link: IntEnz 2.3.1.45
MEDLINE Enzyme Link: MEDLINE 2.3.1.45
MSA:

2.3.1.45;

Phylogenetic Tree:

2.3.1.45;

Uniprot:
M-CSA:
RHEA:26043 acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-9-O-acetylneuraminate
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate.Baumann AM, Bakkers MJ, Buettner FF, Hartmann M, Grove M, Langereis MA, de Groot RJ, Mühlenhoff M2015 Jul 1426169044

RHEA:20808 acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-7-O-acetylneuraminate
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[O;H0;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate.Baumann AM, Bakkers MJ, Buettner FF, Hartmann M, Grove M, Langereis MA, de Groot RJ, Mühlenhoff M2015 Jul 1426169044