| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.45 |
|---|---|
| Description: | N-acetylneuraminate 7-O(or 9-O)-acetyltransferase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.3.1.45 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.45 |
| KEGG Enzyme Link: | KEGG2.3.1.45 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.45 |
| ExPASy Enzyme Link: | ExPASy2.3.1.45 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.45 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.45 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.45 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.45 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.45 |
| RHEA:26043 | acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-9-O-acetylneuraminate |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[O;H0;+0:2]-[*:1] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate. | Baumann AM, Bakkers MJ, Buettner FF, Hartmann M, Grove M, Langereis MA, de Groot RJ, Mühlenhoff M | 2015 Jul 14 | 26169044 |
| RHEA:20808 | acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-7-O-acetylneuraminate |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[O;H0;+0:2]-[*:1] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate. | Baumann AM, Bakkers MJ, Buettner FF, Hartmann M, Grove M, Langereis MA, de Groot RJ, Mühlenhoff M | 2015 Jul 14 | 26169044 |