EC number:2.3.1.76
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.76 |
|---|---|
| Description: | Retinol O-fatty-acyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.76 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.76 |
| KEGG Enzyme Link: | KEGG2.3.1.76 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.76 |
| ExPASy Enzyme Link: | ExPASy2.3.1.76 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.76 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.76 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.76 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.76 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.76 |
| RHEA:11488 | all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[SH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A: retinol acyltransferase. | Ross AC | 1982 Mar 10 | 7061433 |
| Retinol esterification by microsomes from the mucosa of human small intestine. Evidence for acyl-Coenzyme A retinol acyltransferase activity. | Helgerud P, Petersen LB, Norum KR | 1983 Mar | 6826734 |
| Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1. | Orland MD, Anwar K, Cromley D, Chu CH, Chen L, Billheimer JT, Hussain MM, Cheng D | 2005 Oct 15 | 16214399 |
| A human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters. | Yen CL, Brown CH 4th, Monetti M, Farese RV Jr | 2005 Nov | 16106050 |
| Acyl CoA:retinol acyltransferase (ARAT) activity is present in bovine retinal pigment epithelium. | Kaschula CH, Jin MH, Desmond-Smith NS, Travis GH | 2006 Jan | 16054134 |