EC number:2.3.1.78
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.3 Acyltransferases |
| 2.3.1 Transferring groups other than aminoacyl groups |
| ID: | 2.3.1.78 |
|---|---|
| Description: | Heparan-alpha-glucosaminide N-acetyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.3.1.78 |
| BRENDA Enzyme Link: | BRENDA 2.3.1.78 |
| KEGG Enzyme Link: | KEGG2.3.1.78 |
| BioCyc Enzyme Link: | BioCyc 2.3.1.78 |
| ExPASy Enzyme Link: | ExPASy2.3.1.78 |
| EC2PDB Enzyme Link: | EC2PDB 2.3.1.78 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.3.1.78 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.3.1.78 |
| IntEnz Enzyme Link: | IntEnz 2.3.1.78 |
| MEDLINE Enzyme Link: | MEDLINE 2.3.1.78 |
| RHEA:15125 | acetyl-CoA + alpha-D-glucosaminyl-[heparan sulfate](n) = CoA + H(+) + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[S;H0;+0:6]-[*:7]>>[*:7]-[SH;+0:6].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Acetyl coenzyme A: alpha-glucosaminide N-acetyltransferase. Evidence for a transmembrane acetylation mechanism. | Bame KJ, Rome LH | 1985 Sep 15 | 3897232 |
| Acetyl-coenzyme A:alpha-glucosaminide N-acetyltransferase. Evidence for an active site histidine residue. | Bame KJ, Rome LH | 1986 Aug 5 | 3733705 |
| Acetyl-CoA: alpha-glucosaminide N-acetyltransferase from rat liver. | Bame KJ, Rome LH | 1987 | 3298954 |
| Identification of the gene encoding the enzyme deficient in mucopolysaccharidosis IIIC (Sanfilippo disease type C). | Fan X, Zhang H, Zhang S, Bagshaw RD, Tropak MB, Callahan JW, Mahuran DJ | 2006 Oct | 16960811 |