Enzyme

Download
EC Tree
     None
        None
            None
ID:2.3.1.n6
Description:1-acylglycerophosphoserine O-acyltransferase.
Alternative Name: Lysophosphatidylserine acyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

RHEA:33191 a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[S;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[SH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2.Cao J, Shan D, Revett T, Li D, Wu L, Liu W, Tobin JF, Gimeno RE2008 Jul 418458083
Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes.Soupene E, Fyrst H, Kuypers FA2008 Jan 818156367
Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils.Gijón MA, Riekhof WR, Zarini S, Murphy RC, Voelker DR2008 Oct 3118772128
Drosophila lysophospholipid acyltransferases are specifically required for germ cell development.Steinhauer J, Gijón MA, Riekhof WR, Voelker DR, Murphy RC, Treisman JE2009 Dec19864461
Member of the membrane-bound O-acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity.Matsuda S, Inoue T, Lee HC, Kono N, Tanaka F, Gengyo-Ando K, Mitani S, Arai H2008 Aug18782225
Identification of a novel lysophospholipid acyltransferase in Saccharomyces cerevisiae.Jain S, Stanford N, Bhagwat N, Seiler B, Costanzo M, Boone C, Oelkers P2007 Oct 1917726007