EC number:2.3.3.11

Enzyme

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     2. Transferases
        2.3 Acyltransferases
            2.3.3 Acyl groups converted into alkyl groups on transfer
ID:2.3.3.11
Description:2-hydroxyglutarate synthase.
Alternative Name: Hydroxyglutarate synthase.
Alpha-hydroxyglutarate synthase.
2-hydroxyglutaric synthetase.
2-hydroxyglutaratic synthetase.
2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating).

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.3.3.11
BRENDA Enzyme Link: BRENDA 2.3.3.11
KEGG Enzyme Link: KEGG2.3.3.11
BioCyc Enzyme Link: BioCyc 2.3.3.11
ExPASy Enzyme Link: ExPASy2.3.3.11
EC2PDB Enzyme Link: EC2PDB 2.3.3.11
ExplorEnz Enzyme Link: ExplorEnz 2.3.3.11
PRIAM enzyme-specific profiles Link: PRIAM 2.3.3.11
IntEnz Enzyme Link: IntEnz 2.3.3.11
MEDLINE Enzyme Link: MEDLINE 2.3.3.11

EC number:2.3.3.11

MSA:

2.3.3.11;
Phylogenetic Tree:

2.3.3.11;
Uniprot:
M-CSA:
RHEA:19185 glyoxylate + H2O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+)
RULE(radius=1) [*:1]-[CH;+0:2]=[O;H0;+0:3].[*:4]=[C;H0;+0:5](-[*:6]-[CH3;+0:7])-[S;H0;+0:8]-[*:9].[OH2;+0:10]>>[*:9]-[SH;+0:8].[*:4]=[C;H0;+0:5](-[OH;+0:10])-[*:6]-[CH2;+0:7]-[CH;+0:2](-[*:1])-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Alpha-hydroxyglutaric acid synthetase.REEVES HC, AJL SJ1962 Jul14491016