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2. Transferases

2.4 Glycosyltransferases

2.4.2 Pentosyltransferases

ID:

2.4.2.14

Description:

Amidophosphoribosyltransferase.

Alternative Name:

Phosphoribosyldiphosphate 5-amidotransferase.
Glutamine phosphoribosylpyrophosphate amidotransferase.

Prosite:

PDOC00406; PDOC00096;

PDB:

PDB	Scop

Cath:

3.60.20.10; 3.40.50.20; 3.40.50.2020;

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UniProtKB Enzyme Link:	UniProtKB 2.4.2.14
BRENDA Enzyme Link:	BRENDA 2.4.2.14
KEGG Enzyme Link:	KEGG2.4.2.14
BioCyc Enzyme Link:	BioCyc 2.4.2.14
ExPASy Enzyme Link:	ExPASy2.4.2.14
EC2PDB Enzyme Link:	EC2PDB 2.4.2.14
ExplorEnz Enzyme Link:	ExplorEnz 2.4.2.14
PRIAM enzyme-specific profiles Link:	PRIAM 2.4.2.14
IntEnz Enzyme Link:	IntEnz 2.4.2.14
MEDLINE Enzyme Link:	MEDLINE 2.4.2.14

RHEA:14905	5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine
RULE(radius=1)	[:1]-[CH;+0:2](-[:3])-[NH2;+0:4].[:5]-[OH;+0:6].[:7]=[C;H0;+0:8](-[:9])-[OH;+0:10]>>[:1]-[CH;+0:2](-[:3])-[O;H0;+0:6]-[:5].[:7]=[C;H0;+0:8](-[:9])-[NH2;+0:4].[OH2;+0:10]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Purification and properties of glutamine phosphoribosylpyrophosphate amidotransferase from Bacillus subtilis.	Wong JY, Bernlohr DA, Turnbough CL, Switzer RL	1981 Sep 29	6794613
Glutamine phosphoribosylpyrophosphate amidotransferase from Escherichia coli. Purification and properties.	Messenger LJ, Zalkin H	1979 May 10	372191
Chemical genetic identification of glutamine phosphoribosylpyrophosphate amidotransferase as the target for a novel bleaching herbicide in Arabidopsis.	Walsh TA, Bauer T, Neal R, Merlo AO, Schmitzer PR, Hicks GR, Honma M, Matsumura W, Wolff K, Davies JP	2007 Jul	17616508