EC number:2.4.2.4
| ID: | 2.4.2.4 | ||
|---|---|---|---|
| Description: | Thymidine phosphorylase. | ||
| Alternative Name: |
Pyrimidine phosphorylase. | ||
| Prosite: | PDOC00557; | ||
| PDB: |
|
||
| Cath: | 3.40.1030.10; 3.90.1170.30; 1.20.970.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.2.4 |
| BRENDA Enzyme Link: | BRENDA 2.4.2.4 |
| KEGG Enzyme Link: | KEGG2.4.2.4 |
| BioCyc Enzyme Link: | BioCyc 2.4.2.4 |
| ExPASy Enzyme Link: | ExPASy2.4.2.4 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.2.4 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.2.4 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.2.4 |
| IntEnz Enzyme Link: | IntEnz 2.4.2.4 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.2.4 |
| RHEA:16037 | phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[n;H0;+0:4](:[*:5]):[*:6].[*:7]-[OH;+0:8]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:8]-[*:7].[*:5]:[nH;+0:4]:[*:6] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation. | Pugmire MJ, Ealick SE | 1998 Nov 15 | 9817849 |
| Molecular cloning and expression of the pyrimidine nucleoside phosphorylase gene from Bacillus stearothermophilus TH 6-2. | Okuyama K, Hamamoto T, Noguchi T, Midorikawa Y | 1996 Oct | 8987664 |
| Purification and characterization of purine nucleoside phosphorylase and pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus TH 6-2. | Hamamoto T, Noguchi T, Midorikawa Y | 1996 Jul | 8782414 |
| Purification and comparative properties of a pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus. | Saunders PP, Wilson BA, Saunders GF | 1969 Jul 10 | 4978445 |
| Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli. | Sévin DC, Fuhrer T, Zamboni N, Sauer U | 2017 Feb | 27941785 |