EC number:2.5.1.100

Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.100
Description:Fumigaclavine A dimethylallyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.100
BRENDA Enzyme Link: BRENDA 2.5.1.100
KEGG Enzyme Link: KEGG2.5.1.100
BioCyc Enzyme Link: BioCyc 2.5.1.100
ExPASy Enzyme Link: ExPASy2.5.1.100
EC2PDB Enzyme Link: EC2PDB 2.5.1.100
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.100
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.100
IntEnz Enzyme Link: IntEnz 2.5.1.100
MEDLINE Enzyme Link: MEDLINE 2.5.1.100

EC number:2.5.1.100

MSA:

2.5.1.100;
Phylogenetic Tree:

2.5.1.100;
Uniprot:
M-CSA:
RHEA:34263 dimethylallyl diphosphate + fumigaclavine A = diphosphate + fumigaclavine C
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[CH;+0:4]=[C;H0;+0:5](-[*:6])-[*:7].[*:8]:[cH;+0:9]:[*:10]>>[*:1]-[OH;+0:2].[*:8]:[c;H0;+0:9](:[*:10])-[C;H0;+0:5](-[*:6])(-[*:7])-[CH;+0:4]=[CH2;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Ergot alkaloid biosynthesis in Aspergillus fumigatus. Overproduction and biochemical characterization of a 4-dimethylallyltryptophan N-methyltransferase.Rigbers O, Li SM2008 Oct 318678866
Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1.Unsöld IA, Li SM2006 Jan16397874