Enzyme

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     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.101
Description:N,N'-diacetyllegionaminate synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.101
BRENDA Enzyme Link: BRENDA 2.5.1.101
KEGG Enzyme Link: KEGG2.5.1.101
BioCyc Enzyme Link: BioCyc 2.5.1.101
ExPASy Enzyme Link: ExPASy2.5.1.101
EC2PDB Enzyme Link: EC2PDB 2.5.1.101
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.101
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.101
IntEnz Enzyme Link: IntEnz 2.5.1.101
MEDLINE Enzyme Link: MEDLINE 2.5.1.101
MSA:

2.5.1.101;

Phylogenetic Tree:

2.5.1.101;

Uniprot:
M-CSA:
RHEA:34507 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + H2O + phosphoenolpyruvate = N,N-diacetyllegionaminate + phosphate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[CH2;+0:3])-[O;H0;+0:4]-[P;H0;+0:5](=[*:6])(-[*:7])-[*:8].[*:9]-[CH;+0:10](-[*:11]-[*:12]-[OH;+0:13])-[O;H0;+0:14]-[*:15].[OH2;+0:16]>>([*:1]-[C;H0;+0:2]1(-[OH;+0:4])-[CH2;+0:3]-[CH;+0:10](-[*:9])-[*:11]-[*:12]-[O;H0;+0:13]-1.[*:15]-[OH;+0:14]).[*:6]=[P;H0;+0:5](-[*:7])(-[*:8])-[OH;+0:16]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors.Schoenhofen IC, Vinogradov E, Whitfield DM, Brisson JR, Logan SM2009 Jul19282391
Biosynthesis of CMP-N,N'-diacetyllegionaminic acid from UDP-N,N'-diacetylbacillosamine in Legionella pneumophila.Glaze PA, Watson DC, Young NM, Tanner ME2008 Mar 1118275154