EC number:2.5.1.104

Enzyme

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     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.104
Description:N(1)-aminopropylagmatine synthase.
Alternative Name: Triamine/agmatine aminopropyltransferase.
Agmatine/cadaverine aminopropyl transferase.
Agmatine aminopropyltransferase.
ACAPT.
Cath: 2.30.140.10; 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.104
BRENDA Enzyme Link: BRENDA 2.5.1.104
KEGG Enzyme Link: KEGG2.5.1.104
BioCyc Enzyme Link: BioCyc 2.5.1.104
ExPASy Enzyme Link: ExPASy2.5.1.104
EC2PDB Enzyme Link: EC2PDB 2.5.1.104
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.104
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.104
IntEnz Enzyme Link: IntEnz 2.5.1.104
MEDLINE Enzyme Link: MEDLINE 2.5.1.104

EC number:2.5.1.104

MSA:

2.5.1.104;
Phylogenetic Tree:

2.5.1.104;
Uniprot:
M-CSA:
RHEA:36487 agmatine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + N(1)-aminopropylagmatine + S-methyl-5'-thioadenosine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH2;+0:6]-[*:7]>>[*:7]-[CH2;+0:6]-[NH;+0:2]-[*:1].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
N1-aminopropylagmatine, a new polyamine produced as a key intermediate in polyamine biosynthesis of an extreme thermophile, Thermus thermophilus.Ohnuma M, Terui Y, Tamakoshi M, Mitome H, Niitsu M, Samejima K, Kawashima E, Oshima T2005 Aug 2615983049
The first agmatine/cadaverine aminopropyl transferase: biochemical and structural characterization of an enzyme involved in polyamine biosynthesis in the hyperthermophilic archaeon Pyrococcus furiosus.Cacciapuoti G, Porcelli M, Moretti MA, Sorrentino F, Concilio L, Zappia V, Liu ZJ, Tempel W, Schubot F, Rose JP, Wang BC, Brereton PS, Jenney FE, Adams MW2007 Aug17545282