| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.106 |
|---|---|
| Description: | Tryprostatin B synthase. |
| Alternative Name: |
Brevianamide F prenyltransferase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.5.1.106 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.106 |
| KEGG Enzyme Link: | KEGG2.5.1.106 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.106 |
| ExPASy Enzyme Link: | ExPASy2.5.1.106 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.106 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.106 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.106 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.106 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.106 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:35939 | brevianamide F + dimethylallyl diphosphate = diphosphate + tryprostatin B |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[OH;+0:2].[*:5]:[c;H0;+0:6](:[*:7])-[CH2;+0:3]-[*:4] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1. | Wollinsky B, Ludwig L, Xie X, Li SM | 2012 Dec 14 | 23090579 |
| Overproduction, purification and characterization of FtmPT1, a brevianamide F prenyltransferase from Aspergillus fumigatus. | Grundmann A, Li SM | 2005 Jul | 16000710 |