Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.106
Description:Tryprostatin B synthase.
Alternative Name: Brevianamide F prenyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.106
BRENDA Enzyme Link: BRENDA 2.5.1.106
KEGG Enzyme Link: KEGG2.5.1.106
BioCyc Enzyme Link: BioCyc 2.5.1.106
ExPASy Enzyme Link: ExPASy2.5.1.106
EC2PDB Enzyme Link: EC2PDB 2.5.1.106
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.106
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.106
IntEnz Enzyme Link: IntEnz 2.5.1.106
MEDLINE Enzyme Link: MEDLINE 2.5.1.106
MSA:

2.5.1.106;

Phylogenetic Tree:

2.5.1.106;

Uniprot:
M-CSA:
RHEA:35939 brevianamide F + dimethylallyl diphosphate = diphosphate + tryprostatin B
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[OH;+0:2].[*:5]:[c;H0;+0:6](:[*:7])-[CH2;+0:3]-[*:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1.Wollinsky B, Ludwig L, Xie X, Li SM2012 Dec 1423090579
Overproduction, purification and characterization of FtmPT1, a brevianamide F prenyltransferase from Aspergillus fumigatus.Grundmann A, Li SM2005 Jul16000710