EC number:2.5.1.109

Enzyme

Download
EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.109
Description:Brevianamide F prenyltransferase (deoxybrevianamide E-forming).
Alternative Name: Brevianamide F reverse prenyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.109
BRENDA Enzyme Link: BRENDA 2.5.1.109
KEGG Enzyme Link: KEGG2.5.1.109
BioCyc Enzyme Link: BioCyc 2.5.1.109
ExPASy Enzyme Link: ExPASy2.5.1.109
EC2PDB Enzyme Link: EC2PDB 2.5.1.109
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.109
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.109
IntEnz Enzyme Link: IntEnz 2.5.1.109
MEDLINE Enzyme Link: MEDLINE 2.5.1.109

EC number:2.5.1.109

MSA:

2.5.1.109;
Phylogenetic Tree:

2.5.1.109;
Uniprot:
M-CSA:
RHEA:35943 brevianamide F + dimethylallyl diphosphate = deoxybrevianamide E + diphosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[CH;+0:4]=[C;H0;+0:5](-[*:6])-[*:7].[*:8]:[cH;+0:9]:[*:10]>>[*:1]-[OH;+0:2].[*:8]:[c;H0;+0:9](:[*:10])-[C;H0;+0:5](-[*:6])(-[*:7])-[CH;+0:4]=[CH2;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp.Ding Y, de Wet JR, Cavalcoli J, Li S, Greshock TJ, Miller KA, Finefield JM, Sunderhaus JD, McAfoos TJ, Tsukamoto S, Williams RM, Sherman DH2010 Sep 1520722388