EC number:2.5.1.111
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.111 |
|---|---|
| Description: | 4-hydroxyphenylpyruvate 3-dimethylallyltransferase. |
| Alternative Name: |
4HPP dimethylallyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.111 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.111 |
| KEGG Enzyme Link: | KEGG2.5.1.111 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.111 |
| ExPASy Enzyme Link: | ExPASy2.5.1.111 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.111 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.111 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.111 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.111 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.111 |
EC number:2.5.1.111
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:37055 | 3-(4-hydroxyphenyl)pyruvate + dimethylallyl diphosphate = 3-dimethylallyl-4-hydroxyphenylpyruvate + diphosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[CH2;+0:2]-[c;H0;+0:6](:[*:5]):[*:7].[*:4]-[OH;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structure and mechanism of the magnesium-independent aromatic prenyltransferase CloQ from the clorobiocin biosynthetic pathway. | Metzger U, Keller S, Stevenson CE, Heide L, Lawson DM | 2010 Dec 10 | 20946900 |
| NovQ is a prenyltransferase capable of catalyzing the addition of a dimethylallyl group to both phenylpropanoids and flavonoids. | Ozaki T, Mishima S, Nishiyama M, Kuzuyama T | 2009 Jul | 19557032 |
| Crystallization and preliminary X-ray analysis of the aromatic prenyltransferase CloQ from the clorobiocin biosynthetic cluster of Streptomyces roseochromogenes. | Keller S, Pojer F, Heide L, Lawson DM | 2006 Nov 1 | 17077503 |
| CloR, a bifunctional non-heme iron oxygenase involved in clorobiocin biosynthesis. | Pojer F, Kahlich R, Kammerer B, Li SM, Heide L | 2003 Aug 15 | 12777382 |
| CloQ, a prenyltransferase involved in clorobiocin biosynthesis. | Pojer F, Wemakor E, Kammerer B, Chen H, Walsh CT, Li SM, Heide L | 2003 Mar 4 | 12618544 |