EC number:2.5.1.115

Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.115
Description:Homogentisate phytyltransferase.
Alternative Name: HPT.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.115
BRENDA Enzyme Link: BRENDA 2.5.1.115
KEGG Enzyme Link: KEGG2.5.1.115
BioCyc Enzyme Link: BioCyc 2.5.1.115
ExPASy Enzyme Link: ExPASy2.5.1.115
EC2PDB Enzyme Link: EC2PDB 2.5.1.115
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.115
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.115
IntEnz Enzyme Link: IntEnz 2.5.1.115
MEDLINE Enzyme Link: MEDLINE 2.5.1.115

EC number:2.5.1.115

MSA:

2.5.1.115;
Phylogenetic Tree:

2.5.1.115;
Uniprot:
M-CSA:
RHEA:37975 H(+) + homogentisate + phytyl diphosphate = 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]=[C;H0;+0:6](-[OH;+0:7])-[CH2;+0:8]-[*:9]:[*:10]:[cH;+0:11]:[*:12].[H+;H0:13]>>[*:1]-[CH2;+0:2]-[c;H0;+0:11](:[*:12]):[*:10]:[*:9]-[CH3;+0:8].[*:4]-[OH;+0:3].[*:5]=[C;H0;+0:6]=[O;H0;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Vitamin E biosynthesis: functional characterization of the monocot homogentisate geranylgeranyl transferase.Yang W, Cahoon RE, Hunter SC, Zhang C, Han J, Borgschulte T, Cahoon EB2011 Jan21223386
Isolation and functional analysis of homogentisate phytyltransferase from Synechocystis sp. PCC 6803 and Arabidopsis.Collakova E, DellaPenna D2001 Nov11706191