EC number:2.5.1.116

Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.116
Description:Homogentisate geranylgeranyltransferase.
Alternative Name: HGGT.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.116
BRENDA Enzyme Link: BRENDA 2.5.1.116
KEGG Enzyme Link: KEGG2.5.1.116
BioCyc Enzyme Link: BioCyc 2.5.1.116
ExPASy Enzyme Link: ExPASy2.5.1.116
EC2PDB Enzyme Link: EC2PDB 2.5.1.116
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.116
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.116
IntEnz Enzyme Link: IntEnz 2.5.1.116
MEDLINE Enzyme Link: MEDLINE 2.5.1.116

EC number:2.5.1.116

MSA:

2.5.1.116;
Phylogenetic Tree:

2.5.1.116;
Uniprot:
M-CSA:
RHEA:38003 all-trans-geranylgeranyl diphosphate + H(+) + homogentisate = 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]=[C;H0;+0:6](-[OH;+0:7])-[CH2;+0:8]-[*:9]:[*:10]:[cH;+0:11]:[*:12].[H+;H0:13]>>[*:1]-[CH2;+0:2]-[c;H0;+0:11](:[*:12]):[*:10]:[*:9]-[CH3;+0:8].[*:4]-[OH;+0:3].[*:5]=[C;H0;+0:6]=[O;H0;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Vitamin E biosynthesis: functional characterization of the monocot homogentisate geranylgeranyl transferase.Yang W, Cahoon RE, Hunter SC, Zhang C, Han J, Borgschulte T, Cahoon EB2011 Jan21223386
Isolation and functional analysis of homogentisate phytyltransferase from Synechocystis sp. PCC 6803 and Arabidopsis.Collakova E, DellaPenna D2001 Nov11706191