| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.126 |
|---|---|
| Description: | Norspermine synthase. |
| Alternative Name: |
Long-chain polyamine synthase. |
| Cath: | 2.30.140.10; 3.40.50.150; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.5.1.126 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.126 |
| KEGG Enzyme Link: | KEGG2.5.1.126 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.126 |
| ExPASy Enzyme Link: | ExPASy2.5.1.126 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.126 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.126 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.126 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.126 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.126 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:42864 | norspermidine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + norspermine + S-methyl-5'-thioadenosine |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH2;+0:6]-[*:7]>>[*:7]-[CH2;+0:6]-[NH;+0:2]-[*:1].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of propylamine transferase from Sulfolobus solfataricus, an extreme thermophilic archaebacterium. | Cacciapuoti G, Porcelli M, Cartenì-Farina M, Gambacorta A, Zappia V | 1986 Dec 1 | 3096734 |
| Biosynthesis of long-chain polyamines by crenarchaeal polyamine synthases from Hyperthermus butylicus and Pyrobaculum aerophilum. | Knott JM | 2009 Nov 3 | 19822146 |