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2. Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

ID:	2.5.1.128
Description:	N(4)-bis(aminopropyl)spermidine synthase.
Cath:	1.10.10.10; 3.40.50.150;

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UniProtKB Enzyme Link:	UniProtKB 2.5.1.128
BRENDA Enzyme Link:	BRENDA 2.5.1.128
KEGG Enzyme Link:	KEGG2.5.1.128
BioCyc Enzyme Link:	BioCyc 2.5.1.128
ExPASy Enzyme Link:	ExPASy2.5.1.128
EC2PDB Enzyme Link:	EC2PDB 2.5.1.128
ExplorEnz Enzyme Link:	ExplorEnz 2.5.1.128
PRIAM enzyme-specific profiles Link:	PRIAM 2.5.1.128
IntEnz Enzyme Link:	IntEnz 2.5.1.128
MEDLINE Enzyme Link:	MEDLINE 2.5.1.128

RHEA:44132	2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = 2 H(+) + N(4)-bis(aminopropyl)spermidine + 2 S-methyl-5'-thioadenosine
RULE(radius=1)	[:1]-[NH;+0:2]-[:3].[:4]-[S+;H0:5](-[:6])-[CH2;+0:7]-[:8].[:9]-[S+;H0:10](-[:11])-[CH2;+0:12]-[:13]>>[:8]-[CH2;+0:7]-[N+;H0:2](-[:1])(-[:3])-[CH2;+0:12]-[:13].[:4]-[S;H0;+0:5]-[:6].[:9]-[S;H0;+0:10]-[:11]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Identification of a novel aminopropyltransferase involved in the synthesis of branched-chain polyamines in hyperthermophiles.	Okada K, Hidese R, Fukuda W, Niitsu M, Takao K, Horai Y, Umezawa N, Higuchi T, Oshima T, Yoshikawa Y, Imanaka T, Fujiwara S	2014 May	24610711