Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.134
Description:Cystathionine beta-synthase (O-acetyl-L-serine).
Alternative Name: O-acetylserine dependent cystathionine beta-synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.134
BRENDA Enzyme Link: BRENDA 2.5.1.134
KEGG Enzyme Link: KEGG2.5.1.134
BioCyc Enzyme Link: BioCyc 2.5.1.134
ExPASy Enzyme Link: ExPASy2.5.1.134
EC2PDB Enzyme Link: EC2PDB 2.5.1.134
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.134
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.134
IntEnz Enzyme Link: IntEnz 2.5.1.134
MEDLINE Enzyme Link: MEDLINE 2.5.1.134
MSA:

2.5.1.134;

Phylogenetic Tree:

2.5.1.134;

Uniprot:
M-CSA:
RHEA:32743 L-homocysteine + O-acetyl-L-serine = acetate + H(+) + L,L-cystathionine
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[SH;+0:6]>>[*:4]-[OH;+0:3].[*:5]-[S;H0;+0:6]-[CH2;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Conversion of methionine to cysteine in Bacillus subtilis and its regulation.Hullo MF, Auger S, Soutourina O, Barzu O, Yvon M, Danchin A, Martin-Verstraete I2007 Jan17056751