EC number:2.5.1.135

Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.135
Description:Validamine 7-phosphate valienyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.135
BRENDA Enzyme Link: BRENDA 2.5.1.135
KEGG Enzyme Link: KEGG2.5.1.135
BioCyc Enzyme Link: BioCyc 2.5.1.135
ExPASy Enzyme Link: ExPASy2.5.1.135
EC2PDB Enzyme Link: EC2PDB 2.5.1.135
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.135
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.135
IntEnz Enzyme Link: IntEnz 2.5.1.135
MEDLINE Enzyme Link: MEDLINE 2.5.1.135

EC number:2.5.1.135

MSA:

2.5.1.135;
Phylogenetic Tree:

2.5.1.135;
Uniprot:
M-CSA:
RHEA:32119 GDP-valienol + validamine 7-phosphate = GDP + H(+) + validoxylamine A 7'-phosphate
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[O;H0;+0:4]-[CH;+0:5](-[*:6])-[*:7]>>[*:6]-[CH;+0:5](-[*:7])-[NH;+0:2]-[*:1].[*:3]-[OH;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the entire product complex.Cavalier MC, Yim YS, Asamizu S, Neau D, Almabruk KH, Mahmud T, Lee YH201223028689
Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis.Zheng L, Zhou X, Zhang H, Ji X, Li L, Huang L, Bai L, Zhang H201222384130
Pseudoglycosyltransferase catalyzes nonglycosidic C-N coupling in validamycin a biosynthesis.Asamizu S, Yang J, Almabruk KH, Mahmud T2011 Aug 1021766819