EC number:2.5.1.136
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.136 |
|---|---|
| Description: | 2-acylphloroglucinol 4-prenyltransferase. |
| Alternative Name: |
Aromatic prenyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.136 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.136 |
| KEGG Enzyme Link: | KEGG2.5.1.136 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.136 |
| ExPASy Enzyme Link: | ExPASy2.5.1.136 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.136 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.136 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.136 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.136 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.136 |
EC number:2.5.1.136
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:51752 | a 2-acylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4-prenylphloroglucinol + diphosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[CH2;+0:2]-[c;H0;+0:6](:[*:5]):[*:7].[*:4]-[OH;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A heteromeric membrane-bound prenyltransferase complex from hop catalyzes three sequential aromatic prenylations in the bitter acid pathway. | Li H, Ban Z, Qin H, Ma L, King AJ, Wang G | 2015 Mar | 25564559 |
| HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops. | Tsurumaru Y, Sasaki K, Miyawaki T, Uto Y, Momma T, Umemoto N, Momose M, Yazaki K | 2012 Jan 6 | 22166201 |
| RHEA:51764 | dimethylallyl diphosphate + phlorisovalerophenone = 4-prenylphlorisovalerophenone + diphosphate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:4]-[CH2;+0:3]-[c;H0;+0:6](:[*:5]):[*:7].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A heteromeric membrane-bound prenyltransferase complex from hop catalyzes three sequential aromatic prenylations in the bitter acid pathway. | Li H, Ban Z, Qin H, Ma L, King AJ, Wang G | 2015 Mar | 25564559 |
| HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops. | Tsurumaru Y, Sasaki K, Miyawaki T, Uto Y, Momma T, Umemoto N, Momose M, Yazaki K | 2012 Jan 6 | 22166201 |
| RHEA:51768 | 2-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one + dimethylallyl diphosphate = 4-prenylphlormethylbutanophenone + diphosphate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[OH;+0:2].[*:5]:[c;H0;+0:6](:[*:7])-[CH2;+0:3]-[*:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A heteromeric membrane-bound prenyltransferase complex from hop catalyzes three sequential aromatic prenylations in the bitter acid pathway. | Li H, Ban Z, Qin H, Ma L, King AJ, Wang G | 2015 Mar | 25564559 |
| HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops. | Tsurumaru Y, Sasaki K, Miyawaki T, Uto Y, Momma T, Umemoto N, Momose M, Yazaki K | 2012 Jan 6 | 22166201 |
| RHEA:51772 | 2-methyl-1-(2,4,6-trihydroxyphenyl)propan-1-one + dimethylallyl diphosphate = 4-prenylphlorisobutanophenone + diphosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[CH2;+0:2]-[c;H0;+0:6](:[*:5]):[*:7].[*:4]-[OH;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A heteromeric membrane-bound prenyltransferase complex from hop catalyzes three sequential aromatic prenylations in the bitter acid pathway. | Li H, Ban Z, Qin H, Ma L, King AJ, Wang G | 2015 Mar | 25564559 |
| HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops. | Tsurumaru Y, Sasaki K, Miyawaki T, Uto Y, Momma T, Umemoto N, Momose M, Yazaki K | 2012 Jan 6 | 22166201 |
| RHEA:51876 | 2',4,4',6'-tetrahydroxychalcone + dimethylallyl diphosphate = desmethylxanthohumol + diphosphate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[OH;+0:2].[*:5]:[c;H0;+0:6](:[*:7])-[CH2;+0:3]-[*:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A heteromeric membrane-bound prenyltransferase complex from hop catalyzes three sequential aromatic prenylations in the bitter acid pathway. | Li H, Ban Z, Qin H, Ma L, King AJ, Wang G | 2015 Mar | 25564559 |
| HlPT-1, a membrane-bound prenyltransferase responsible for the biosynthesis of bitter acids in hops. | Tsurumaru Y, Sasaki K, Miyawaki T, Uto Y, Momma T, Umemoto N, Momose M, Yazaki K | 2012 Jan 6 | 22166201 |