EC number:2.5.1.140

Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.140
Description:N-(2-amino-2-carboxyethyl)-L-glutamate synthase.
Alternative Name: ACEGA synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.140
BRENDA Enzyme Link: BRENDA 2.5.1.140
KEGG Enzyme Link: KEGG2.5.1.140
BioCyc Enzyme Link: BioCyc 2.5.1.140
ExPASy Enzyme Link: ExPASy2.5.1.140
EC2PDB Enzyme Link: EC2PDB 2.5.1.140
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.140
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.140
IntEnz Enzyme Link: IntEnz 2.5.1.140
MEDLINE Enzyme Link: MEDLINE 2.5.1.140

EC number:2.5.1.140

MSA:

2.5.1.140;
Phylogenetic Tree:

2.5.1.140;
Uniprot:
M-CSA:
RHEA:52384 L-glutamate + O-phospho-L-serine = H(+) + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[NH2;+0:6]>>[*:5]-[NH;+0:6]-[CH2;+0:2]-[*:1].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor.Kobylarz MJ, Grigg JC, Takayama SJ, Rai DK, Heinrichs DE, Murphy ME2014 Mar 2024485762
Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus.Beasley FC, Cheung J, Heinrichs DE2011 Sep 921906287
Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis.Kobylarz MJ, Grigg JC, Liu Y, Lee MS, Heinrichs DE, Murphy ME2016 Feb 1626794841