EC number:2.5.1.145

Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.145
Description:Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.145
BRENDA Enzyme Link: BRENDA 2.5.1.145
KEGG Enzyme Link: KEGG2.5.1.145
BioCyc Enzyme Link: BioCyc 2.5.1.145
ExPASy Enzyme Link: ExPASy2.5.1.145
EC2PDB Enzyme Link: EC2PDB 2.5.1.145
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.145
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.145
IntEnz Enzyme Link: IntEnz 2.5.1.145
MEDLINE Enzyme Link: MEDLINE 2.5.1.145

EC number:2.5.1.145

MSA:

2.5.1.145;
Phylogenetic Tree:

2.5.1.145;
Uniprot:
M-CSA:
RHEA:56712 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + [prolipoprotein]-L-cysteine = [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine + H(+) + sn-glycerol 1-phosphate
RULE(radius=1)
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Roles of histidine-103 and tyrosine-235 in the function of the prolipoprotein diacylglyceryl transferase of Escherichia coli.Sankaran K, Gan K, Rash B, Qi HY, Wu HC, Rick PD1997 May9139912
Lipid modification of bacterial prolipoprotein. Transfer of diacylglyceryl moiety from phosphatidylglycerol.Sankaran K, Wu HC1994 Aug 58051048
The umpA gene of Escherichia coli encodes phosphatidylglycerol:prolipoprotein diacylglyceryl transferase (lgt) and regulates thymidylate synthase levels through translational coupling.Gan K, Sankaran K, Williams MG, Aldea M, Rudd KE, Kushner SR, Wu HC1995 Apr7896715
Structure-function relationship of bacterial prolipoprotein diacylglyceryl transferase: functionally significant conserved regions.Qi HY, Sankaran K, Gan K, Wu HC1995 Dec7592473
Phosphatidylglycerol::prolipoprotein diacylglyceryl transferase (Lgt) of Escherichia coli has seven transmembrane segments, and its essential residues are embedded in the membrane.Pailler J, Aucher W, Pires M, Buddelmeijer N2012 May22287519