Enzyme

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     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.146
Description:3-geranyl-3-((Z)-2-isocyanoethenyl)indole synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.146
BRENDA Enzyme Link: BRENDA 2.5.1.146
KEGG Enzyme Link: KEGG2.5.1.146
BioCyc Enzyme Link: BioCyc 2.5.1.146
ExPASy Enzyme Link: ExPASy2.5.1.146
EC2PDB Enzyme Link: EC2PDB 2.5.1.146
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.146
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.146
IntEnz Enzyme Link: IntEnz 2.5.1.146
MEDLINE Enzyme Link: MEDLINE 2.5.1.146
MSA:

2.5.1.146;

Phylogenetic Tree:

2.5.1.146;

Uniprot:
M-CSA:
RHEA:17349 (2E)-geranyl diphosphate + 3-[(Z)-2-isocyanoethenyl]-1H-indole = 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + diphosphate
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[c;H0;+0:6]1:[*:7]:[*:8]:[nH;+0:9]:[cH;+0:10]:1>>[*:1]-[CH2;+0:2]-[C;H0;+0:6]1(-[*:5])-[*:7]:[*:8]-[N;H0;+0:9]=[CH;+0:10]-1.[*:4]-[OH;+0:3]
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References

TitleAuthorsDatePubMed ID
Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids.Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH2017 May28288107