EC number:2.5.1.26
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.26 |
|---|---|
| Description: | Alkylglycerone-phosphate synthase. |
| Alternative Name: |
Alkyldihydroxyacetonephosphate synthase. Alkyl-DHAP synthase. |
| Cath: | 1.10.45.10; 3.30.160.650; 3.30.300.330; 3.30.43.10; 3.30.465.10; 3.30.465.40; 3.30.70.3450; 3.40.462.40; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.26 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.26 |
| KEGG Enzyme Link: | KEGG2.5.1.26 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.26 |
| ExPASy Enzyme Link: | ExPASy2.5.1.26 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.26 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.26 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.26 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.26 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.26 |
| RHEA:36171 | a 1-acylglycerone 3-phosphate + a long chain fatty alcohol = 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[OH;+0:6]>>[*:5]-[O;H0;+0:6]-[CH2;+0:3]-[*:4].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of recombinant guinea pig alkyl-dihydroxyacetonephosphate synthase expressed in Escherichia coli. Kinetics, chemical modification and mutagenesis. | de Vet EC, van den Bosch H | 1999 Jan 4 | 9989261 |
| Alkyl-dihydroxyacetonephosphate synthase. Fate in peroxisome biogenesis disorders and identification of the point mutation underlying a single enzyme deficiency. | de Vet EC, Ijlst L, Oostheim W, Wanders RJ, van den Bosch H | 1998 Apr 24 | 9553082 |
| Ether lipid synthesis: purification and identification of alkyl dihydroxyacetone phosphate synthase from guinea-pig liver. | Zomer AW, de Weerd WF, Langeveld J, van den Bosch H | 1993 Oct 13 | 8399344 |
| The mechanism of alkyldihydroxyacetone-P synthase. Formation of [3H]H2O from acyl[1-R-3H]dihydroxyacetone-P by purified alkyldihydroxyacetone-P synthase in the absence of acylhydrolase activity. | Brown AJ, Snyder F | 1983 Apr 10 | 6833249 |
| Alkyl-dihydroxyacetonephosphate synthase. Presence and role of flavin adenine dinucleotide. | de Vet EC, Hilkes YH, Fraaije MW, van den Bosch H | 2000 Mar 3 | 10692424 |