Enzyme

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     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.38
Description:Isonocardicin synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.38
BRENDA Enzyme Link: BRENDA 2.5.1.38
KEGG Enzyme Link: KEGG2.5.1.38
BioCyc Enzyme Link: BioCyc 2.5.1.38
ExPASy Enzyme Link: ExPASy2.5.1.38
EC2PDB Enzyme Link: EC2PDB 2.5.1.38
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.38
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.38
IntEnz Enzyme Link: IntEnz 2.5.1.38
MEDLINE Enzyme Link: MEDLINE 2.5.1.38
MSA:

2.5.1.38;

Phylogenetic Tree:

2.5.1.38;

Uniprot:
M-CSA:
RHEA:49708 nocardicin G + S-adenosyl-L-methionine = H(+) + isonocardicin C + S-methyl-5'-thioadenosine
RULE(radius=1) [*:1]-[CH2;+0:2]-[S+;H0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH2;+0:2]-[*:1].[*:4]-[S;H0;+0:3]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification, characterization, and cloning of an S-adenosylmethionine-dependent 3-amino-3-carboxypropyltransferase in nocardicin biosynthesis.Reeve AM, Breazeale SD, Townsend CA1998 Nov 139804844
Mutational analysis of nocK and nocL in the nocardicin a producer Nocardia uniformis.Kelly WL, Townsend CA2005 Jan15629944

RHEA:19845 nocardicin E + S-adenosyl-L-methionine = H(+) + isonocardicin A + S-methyl-5'-thioadenosine
RULE(radius=1) [*:1]-[CH2;+0:2]-[S+;H0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH2;+0:2]-[*:1].[*:4]-[S;H0;+0:3]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification, characterization, and cloning of an S-adenosylmethionine-dependent 3-amino-3-carboxypropyltransferase in nocardicin biosynthesis.Reeve AM, Breazeale SD, Townsend CA1998 Nov 139804844
Mutational analysis of nocK and nocL in the nocardicin a producer Nocardia uniformis.Kelly WL, Townsend CA2005 Jan15629944