| Title | Authors | Date | PubMed ID |
|---|
| Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases. | Wilson AL, Erdman RA, Castellano F, Maltese WA | 1998 Aug 1 | 9677305 |
| Plant farnesyltransferase can restore yeast Ras signaling and mating. | Yalovsky S, Trueblood CE, Callan KL, Narita JO, Jenkins SM, Rine J, Gruissem W | 1997 Apr | 9121446 |
| Influence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-I. | Zhang FL, Casey PJ | 1996 Dec 15 | 9003382 |
| Protein farnesyltransferase in plants: molecular characterization and involvement in cell cycle control. | Qian D, Zhou D, Ju R, Cramer CL, Yang Z | 1996 Dec | 8989889 |
| cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase. | Armstrong SA, Seabra MC, Südhof TC, Goldstein JL, Brown MS | 1993 Jun 5 | 8505342 |
| Mutational analysis of alpha-subunit of protein farnesyltransferase. Evidence for a catalytic role. | Andres DA, Goldstein JL, Ho YK, Brown MS | 1993 Jan 15 | 8419339 |
| cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I. | Zhang FL, Diehl RE, Kohl NE, Gibbs JB, Giros B, Casey PJ, Omer CA | 1994 Feb 4 | 8106351 |
| Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A. | Farnsworth CC, Seabra MC, Ericsson LH, Gelb MH, Glomset JA | 1994 Dec 6 | 7991565 |
| Development of selective, potent RabGGTase inhibitors. | Stigter EA, Guo Z, Bon RS, Wu YW, Choidas A, Wolf A, Menninger S, Waldmann H, Blankenfeldt W, Goody RS | 2012 Oct 11 | 22963166 |
| Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase. | Deraeve C, Guo Z, Bon RS, Blankenfeldt W, DiLucrezia R, Wolf A, Menninger S, Stigter EA, Wetzel S, Choidas A, Alexandrov K, Waldmann H, Goody RS, Wu YW | 2012 May 2 | 22480322 |
| Structure-guided development of selective RabGGTase inhibitors. | Bon RS, Guo Z, Stigter EA, Wetzel S, Menninger S, Wolf A, Choidas A, Alexandrov K, Blankenfeldt W, Goody RS, Waldmann H | 2011 May 16 | 21520375 |
| Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors. | Tan KT, Guiu-Rozas E, Bon RS, Guo Z, Delon C, Wetzel S, Arndt S, Alexandrov K, Waldmann H, Goody RS, Wu YW, Blankenfeldt W | 2009 Dec 24 | 19894725 |
| Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. | Nguyen UT, Guo Z, Delon C, Wu Y, Deraeve C, Fränzel B, Bon RS, Blankenfeldt W, Goody RS, Waldmann H, Wolters D, Alexandrov K | 2009 Apr | 19219049 |
| Caged protein prenyltransferase substrates: tools for understanding protein prenylation. | DeGraw AJ, Hast MA, Xu J, Mullen D, Beese LS, Barany G, Distefano MD | 2008 Sep | 18844669 |
| Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. | Guo Z, Wu YW, Das D, Delon C, Cramer J, Yu S, Thuns S, Lupilova N, Waldmann H, Brunsveld L, Goody RS, Alexandrov K, Blankenfeldt W | 2008 Sep 17 | 18756270 |
| Development of selective RabGGTase inhibitors and crystal structure of a RabGGTase-inhibitor complex. | Guo Z, Wu YW, Tan KT, Bon RS, Guiu-Rozas E, Delon C, Nguyen TU, Wetzel S, Arndt S, Goody RS, Blankenfeldt W, Alexandrov K, Waldmann H | 2008 | 18399557 |
| Thematic review series: lipid posttranslational modifications. Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I. | Lane KT, Beese LS | 2006 Apr | 16477080 |
| Protein prenylation: genes, enzymes, targets, and functions. | Schafer WR, Rine J | 1992 | 1482112 |
| Structure of mammalian protein geranylgeranyltransferase type-I. | Taylor JS, Reid TS, Terry KL, Casey PJ, Beese LS | 2003 Nov 17 | 14609943 |
| Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. | Gwaltney SL 2nd, O'Connor SJ, Nelson LT, Sullivan GM, Imade H, Wang W, Hasvold L, Li Q, Cohen J, Gu WZ, Tahir SK, Bauch J, Marsh K, Ng SC, Frost DJ, Zhang H, Muchmore S, Jakob CG, Stoll V, Hutchins C, Rosenberg SH, Sham HL | 2003 Apr 7 | 12657282 |
| In vitro assembly, purification, and crystallization of the rab geranylgeranyl transferase:substrate complex. | Rak A, Niculae A, Kalinin A, Thomä NH, Sidorovitch V, Goody RS, Alexandrov K | 2002 Jun | 12071695 |
| 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. | Bell IM, Gallicchio SN, Abrams M, Beese LS, Beshore DC, Bhimnathwala H, Bogusky MJ, Buser CA, Culberson JC, Davide J, Ellis-Hutchings M, Fernandes C, Gibbs JB, Graham SL, Hamilton KA, Hartman GD, Heimbrook DC, Homnick CF, Huber HE, Huff JR, Kassahun K, Koblan KS, Kohl NE, Lobell RB, Lynch JJ Jr, Robinson R, Rodrigues AD, Taylor JS, Walsh ES, Williams TM, Zartman CB | 2002 Jun 6 | 12036349 |
| Double prenylation by RabGGTase can proceed without dissociation of the mono-prenylated intermediate. | Thomä NH, Niculae A, Goody RS, Alexandrov K | 2001 Dec 28 | 11591706 |
| Efficient prenylation by a plant geranylgeranyltransferase-I requires a functional CaaL box motif and a proximal polybasic domain. | Caldelari D, Sternberg H, Rodríguez-Concepción M, Gruissem W, Yalovsky S | 2001 Aug | 11500541 |
| Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution. | Zhang H, Seabra MC, Deisenhofer J | 2000 Mar 15 | 10745007 |
