EC number:2.5.1.63
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.63 |
|---|---|
| Description: | Adenosyl-fluoride synthase. |
| Alternative Name: |
Fluorinase. |
| Cath: | 2.40.30.90; 3.40.50.10790; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.63 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.63 |
| KEGG Enzyme Link: | KEGG2.5.1.63 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.63 |
| ExPASy Enzyme Link: | ExPASy2.5.1.63 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.63 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.63 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.63 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.63 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.63 |
| RHEA:16661 | fluoride + S-adenosyl-L-methionine = 5'-deoxy-5'-fluoroadenosine + L-methionine |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[S+;H0:3](-[*:4])-[*:5].[F-;H0:6]>>[*:1]-[CH2;+0:2]-[F;H0;+0:6].[*:4]-[S;H0;+0:3]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure and mechanism of a bacterial fluorinating enzyme. | Dong C, Huang F, Deng H, Schaffrath C, Spencer JB, O'Hagan D, Naismith JH | 2004 Feb 5 | 14765200 |
| Biochemistry: biosynthesis of an organofluorine molecule. | O'Hagan D, Schaffrath C, Cobb SL, Hamilton JT, Murphy CD | 2002 Mar 21 | 11907567 |