EC number:2.5.1.65
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.65 |
|---|---|
| Description: | O-phosphoserine sulfhydrylase. |
| Alternative Name: |
O-phosphoserine(thiol)-lyase. |
| Cath: | 3.90.1530.20; 3.40.50.1100; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.65 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.65 |
| KEGG Enzyme Link: | KEGG2.5.1.65 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.65 |
| ExPASy Enzyme Link: | ExPASy2.5.1.65 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.65 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.65 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.65 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.65 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.65 |
| RHEA:10252 | H(+) + hydrogen sulfide + O-phospho-L-serine = L-cysteine + phosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[H+;H0:5].[SH2;+0:6]>>[*:1]-[CH2;+0:2]-[SH;+0:6].[*:4]-[OH;+0:3] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase. | Steiner EM, Böth D, Lössl P, Vilaplana F, Schnell R, Schneider G | 2014 Oct | 25022854 |
| Three-dimensional structure of a new enzyme, O-phosphoserine sulfhydrylase, involved in l-cysteine biosynthesis by a hyperthermophilic archaeon, Aeropyrum pernix K1, at 2.0A resolution. | Oda Y, Mino K, Ishikawa K, Ataka M | 2005 Aug 12 | 16005886 |
| A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1. | Mino K, Ishikawa K | 2003 Sep 11 | 12965218 |
| Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1. | Mino K, Ishikawa K | 2003 Apr | 12644499 |
| Crystallization and preliminary X-ray diffraction analysis of O-acetylserine sulfhydrylase from Aeropyrum pernix K1. | Mino K, Oda Y, Ataka M, Ishikawa K | 2003 Feb | 12554945 |