Enzyme

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EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.66
Description:N(2)-(2-carboxyethyl)arginine synthase.
Alternative Name: N(2)-(2-carboxyethyl)arginine synthetase.
CEAS.
CEA synthetase.
Cath: 3.40.50.970; 3.40.50.1220;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.66
BRENDA Enzyme Link: BRENDA 2.5.1.66
KEGG Enzyme Link: KEGG2.5.1.66
BioCyc Enzyme Link: BioCyc 2.5.1.66
ExPASy Enzyme Link: ExPASy2.5.1.66
EC2PDB Enzyme Link: EC2PDB 2.5.1.66
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.66
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.66
IntEnz Enzyme Link: IntEnz 2.5.1.66
MEDLINE Enzyme Link: MEDLINE 2.5.1.66
MSA:

2.5.1.66;

Phylogenetic Tree:

2.5.1.66;

Uniprot:
M-CSA:
RHEA:10556 D-glyceraldehyde 3-phosphate + L-arginine = H(+) + N(2)-(2-carboxyethyl)-L-arginine + phosphate
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]=[CH;+0:4]-[CH;+0:5](-[OH;+0:6])-[CH2;+0:7]-[O;H0;+0:8]-[*:9]>>[*:9]-[OH;+0:8].[*:3]=[C;H0;+0:4](-[OH;+0:6])-[CH2;+0:5]-[CH2;+0:7]-[NH;+0:2]-[*:1]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Crystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway.Caines ME, Elkins JM, Hewitson KS, Schofield CJ2004 Feb 1314623876