EC number:2.5.1.81
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.81 |
|---|---|
| Description: | Geranylfarnesyl diphosphate synthase. |
| Alternative Name: |
FGPP synthase. |
| Cath: | 1.10.600.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.81 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.81 |
| KEGG Enzyme Link: | KEGG2.5.1.81 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.81 |
| ExPASy Enzyme Link: | ExPASy2.5.1.81 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.81 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.81 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.81 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.81 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.81 |
| RHEA:25694 | all-trans-geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate |
| RULE(radius=1) | [C:1]([CH3:2])=[C:3][C:4][O:0].[CH2:5]=[C:6]([CH3:7])[C:8][C:9][O:10][P:11](=[O:12])([O:13])[O:14]>>[C:1]([CH3:2])=[C:3][C:4][CH2:5][C:6]([CH3:7])=[C:8][C:9][O:0].[O:10][P:11](=[O:12])([O:13])[O:14] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A novel prenyltransferase, farnesylgeranyl diphosphate synthase, from the haloalkaliphilic archaeon, Natronobacterium pharaonis. | Tachibana A | 1994 Mar 21 | 8137956 |
| Geranylfarnesyl diphosphate synthase from Methanosarcina mazei: Different role, different evolution. | Ogawa T, Yoshimura T, Hemmi H | 2010 Feb 26 | 20097171 |
| Alteration of product specificity of Aeropyrum pernix farnesylgeranyl diphosphate synthase (Fgs) by directed evolution. | Lee PC, Mijts BN, Petri R, Watts KT, Schmidt-Dannert C | 2004 Nov | 15548566 |
| Novel prenyltransferase gene encoding farnesylgeranyl diphosphate synthase from a hyperthermophilic archaeon, Aeropyrum pernix. Molecularevolution with alteration in product specificity. | Tachibana A, Yano Y, Otani S, Nomura N, Sako Y, Taniguchi M | 2000 Jan | 10632701 |