EC number:2.5.1.86
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.86 |
|---|---|
| Description: | Trans,polycis-decaprenyl diphosphate synthase. |
| Alternative Name: |
(2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate synthase. |
| Cath: | 3.40.1180.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.86 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.86 |
| KEGG Enzyme Link: | KEGG2.5.1.86 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.86 |
| ExPASy Enzyme Link: | ExPASy2.5.1.86 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.86 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.86 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.86 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.86 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.86 |
| RHEA:47096 | (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate + 7 diphosphate |
| RULE(radius=1) | [C:1]([CH3:2])=[C:3][C:4][O:0].[CH2:5]=[C:6]([CH3:7])[C:8][C:9][O:10][P:11](=[O:12])([O:13])[O:14].[CH2:25]=[C:26]([CH3:27])[C:28][C:29][O:20][P:21](=[O:22])([O:23])[O:24].[CH2:35]=[C:36]([CH3:37])[C:38][C:39][O:30][P:31](=[O:32])([O:33])[O:34].[CH2:45]=[C:46]([CH3:47])[C:48][C:49][O:40][P:41](=[O:42])([O:43])[O:44].[CH2:55]=[C:56]([CH3:57])[C:58][C:59][O:50][P:51](=[O:52])([O:53])[O:54].[CH2:65]=[C:66]([CH3:67])[C:68][C:69][O:60][P:61](=[O:62])([O:63])[O:64].[CH2:75]=[C:76]([CH3:77])[C:78][C:79][O:70][P:71](=[O:72])([O:73])[O:74]>>[C:1]([CH3:2])=[C:3][C:4][CH2:5][C:6]([CH3:7])=[C:8][C:9][CH2:25][C:26]([CH3:27])=[C:28][C:29][CH2:35][C:36]([CH3:37])=[C:38][C:39][CH2:45][C:46]([CH3:47])=[C:48][C:49][CH2:55][C:56]([CH3:57])=[C:58][C:59][CH2:65][C:66]([CH3:67])=[C:68][C:69][CH2:75][C:76]([CH3:77])=[C:78][C:79][O:0].[O:10][P:11](=[O:12])([O:13])[O:14].[O:20][P:21](=[O:22])([O:23])[O:24].[O:30][P:31](=[O:32])([O:33])[O:34].[O:40][P:41](=[O:42])([O:43])[O:44].[O:50][P:51](=[O:52])([O:53])[O:54].[O:60][P:61](=[O:62])([O:63])[O:64].[O:70][P:71](=[O:72])([O:73])[O:74] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The structural basis of chain length control in Rv1086. | Wang W, Dong C, McNeil M, Kaur D, Mahapatra S, Crick DC, Naismith JH | 2008 Aug 1 | 18597781 |
| Decaprenyl diphosphate synthesis in Mycobacterium tuberculosis. | Kaur D, Brennan PJ, Crick DC | 2004 Nov | 15516568 |
| Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis. | Crick DC, Schulbach MC, Zink EE, Macchia M, Barontini S, Besra GS, Brennan PJ | 2000 Oct | 11004176 |