Enzyme

Download
EC Tree
     2. Transferases
        2.5 Transferring alkyl or aryl groups, other than methyl groups
            2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
ID:2.5.1.93
Description:4-hydroxybenzoate geranyltransferase.
Alternative Name: PHB geranyltransferase.
p-hydroxybenzoate geranyltransferase.
4HB geranyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.5.1.93
BRENDA Enzyme Link: BRENDA 2.5.1.93
KEGG Enzyme Link: KEGG2.5.1.93
BioCyc Enzyme Link: BioCyc 2.5.1.93
ExPASy Enzyme Link: ExPASy2.5.1.93
EC2PDB Enzyme Link: EC2PDB 2.5.1.93
ExplorEnz Enzyme Link: ExplorEnz 2.5.1.93
PRIAM enzyme-specific profiles Link: PRIAM 2.5.1.93
IntEnz Enzyme Link: IntEnz 2.5.1.93
MEDLINE Enzyme Link: MEDLINE 2.5.1.93
MSA:

2.5.1.93;

Phylogenetic Tree:

2.5.1.93;

Uniprot:
M-CSA:
RHEA:27854 (2E)-geranyl diphosphate + 4-hydroxybenzoate = 3-geranyl-4-hydroxybenzoate + diphosphate
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[CH2;+0:2]-[c;H0;+0:6](:[*:5]):[*:7].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
4-Hydroxybenzoate 3-geranyltransferase from Lithospermum erythrorhizon: purification of a plant membrane-bound prenyltransferase.Mühlenweg A, Melzer M, Li SM, Heide L1998 Jul9640665
Functional characterization of LePGT1, a membrane-bound prenyltransferase involved in the geranylation of p-hydroxybenzoic acid.Ohara K, Muroya A, Fukushima N, Yazaki K2009 Jun 2619392660
COQ2 is a candidate for the structural gene encoding para-hydroxybenzoate:polyprenyltransferase.Ashby MN, Kutsunai SY, Ackerman S, Tzagoloff A, Edwards PA1992 Feb 251740455
Geranyl diphosphate:4-hydroxybenzoate geranyltransferase from Lithospermum erythrorhizon. Cloning and characterization of a ket enzyme in shikonin biosynthesis.Yazaki K, Kunihisa M, Fujisaki T, Sato F2002 Feb 2211744717