EC number:2.5.1.96
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.5 Transferring alkyl or aryl groups, other than methyl groups |
| 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
| ID: | 2.5.1.96 |
|---|---|
| Description: | 4,4'-diapophytoene synthase. |
| Alternative Name: |
Dehydrosqualene synthase. DAP synthase. C(30) carotene synthase. |
| Cath: | 1.10.600.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.5.1.96 |
| BRENDA Enzyme Link: | BRENDA 2.5.1.96 |
| KEGG Enzyme Link: | KEGG2.5.1.96 |
| BioCyc Enzyme Link: | BioCyc 2.5.1.96 |
| ExPASy Enzyme Link: | ExPASy2.5.1.96 |
| EC2PDB Enzyme Link: | EC2PDB 2.5.1.96 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.96 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.96 |
| IntEnz Enzyme Link: | IntEnz 2.5.1.96 |
| MEDLINE Enzyme Link: | MEDLINE 2.5.1.96 |
| RHEA:31547 | 2 (2E,6E)-farnesyl diphosphate = 15-cis-4,4'-diapophytoene + 2 diphosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[O;H0;+0:6]-[CH2;+0:7]-[*:8]>>[*:1]-[CH;+0:2]=[CH;+0:7]-[*:8].[*:4]-[OH;+0:3].[*:5]-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. | Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E | 2008 Mar 7 | 18276850 |
| Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. | Ku B, Jeong JC, Mijts BN, Schmidt-Dannert C, Dordick JS | 2005 Nov | 16269684 |
| Evolution of the C30 carotenoid synthase CrtM for function in a C40 pathway. | Umeno D, Tobias AV, Arnold FH | 2002 Dec | 12426357 |