| ID: | 2.6.1.100 |
|---|---|
| Description: | L-glutamine:2-deoxy-scyllo-inosose aminotransferase. |
| Cath: | 3.40.640.10; 3.90.1150.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.6.1.100 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.100 |
| KEGG Enzyme Link: | KEGG2.6.1.100 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.100 |
| ExPASy Enzyme Link: | ExPASy2.6.1.100 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.100 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.100 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.100 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.100 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.100 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:34147 | 2-deoxy-L-scyllo-inosose + L-glutamine = 2-deoxy-scyllo-inosamine + 2-oxoglutaramate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Functional characterization of kanB by complementing in engineered Streptomyces fradiae Deltaneo6::tsr. | Jnawali HN, Subba B, Liou K, Sohng JK | 2009 Jun | 19219581 |
| The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine. | Huang F, Haydock SF, Mironenko T, Spiteller D, Li Y, Spencer JB | 2005 Apr 21 | 15827636 |
| A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster. | Kharel MK, Subba B, Basnet DB, Woo JS, Lee HC, Liou K, Sohng JK | 2004 Sep 15 | 15313224 |
| First identification of Streptomyces genes involved in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics--genetic and evolutionary analysis of L-glutamine:2-deoxy-scyllo-inosose aminotransferase genes. | Tamegai H, Eguchi T, Kakinuma K | 2002 Nov | 12546424 |
| Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterisation of an aminotransferase involved in the pathway to 2-deoxystreptamine. | Huang F, Li Y, Yu J, Spencer JB | 2002 Dec 7 | 12478783 |
| Identification of L-glutamine: 2-deoxy-scyllo-inosose aminotransferase required for the biosynthesis of butirosin in Bacillus circulans. | Tamegai H, Nango E, Kuwahara M, Yamamoto H, Ota Y, Kuriki H, Eguchi T, Kakinuma K | 2002 Aug | 12374384 |