EC number:2.6.1.101

Enzyme

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     2. Transferases
        2.6 Transferring nitrogenous groups
            2.6.1 Transaminases
ID:2.6.1.101
Description:L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase.
Cath: 3.40.640.10; 3.90.1150.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.6.1.101
BRENDA Enzyme Link: BRENDA 2.6.1.101
KEGG Enzyme Link: KEGG2.6.1.101
BioCyc Enzyme Link: BioCyc 2.6.1.101
ExPASy Enzyme Link: ExPASy2.6.1.101
EC2PDB Enzyme Link: EC2PDB 2.6.1.101
ExplorEnz Enzyme Link: ExplorEnz 2.6.1.101
PRIAM enzyme-specific profiles Link: PRIAM 2.6.1.101
IntEnz Enzyme Link: IntEnz 2.6.1.101
MEDLINE Enzyme Link: MEDLINE 2.6.1.101

EC number:2.6.1.101

MSA:

2.6.1.101;
Phylogenetic Tree:

2.6.1.101;
Uniprot:
M-CSA:
RHEA:34151 3-amino-2,3-dideoxy-scyllo-inosose + L-glutamine = 2-deoxystreptamine + 2-oxoglutaramate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8]
Reaction
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References

TitleAuthorsDatePubMed ID
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.Kudo F, Yamamoto Y, Yokoyama K, Eguchi T, Kakinuma K2005 Dec16506694
The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.Huang F, Haydock SF, Mironenko T, Spiteller D, Li Y, Spencer JB2005 Apr 2115827636
Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterisation of an aminotransferase involved in the pathway to 2-deoxystreptamine.Huang F, Li Y, Yu J, Spencer JB2002 Dec 712478783
Identification of L-glutamine: 2-deoxy-scyllo-inosose aminotransferase required for the biosynthesis of butirosin in Bacillus circulans.Tamegai H, Nango E, Kuwahara M, Yamamoto H, Ota Y, Kuriki H, Eguchi T, Kakinuma K2002 Aug12374384