EC number:2.6.1.13
| ID: | 2.6.1.13 | ||
|---|---|---|---|
| Description: | Ornithine aminotransferase. | ||
| Alternative Name: |
Ornithine--oxo-acid transaminase. Ornithine--oxo acid aminotransferase. Ornithine--ketoglutarate aminotransferase. Ornithine--keto acid transaminase. Ornithine--keto acid aminotransferase. Ornithine--alpha-ketoglutarate aminotransferase. Ornithine--2-oxoacid aminotransferase. Ornithine transaminase. Ornithine ketoacid aminotransferase. Ornithine delta-transaminase. Ornithine 5-aminotransferase. L-ornithine aminotransferase. L-ornithine 5-aminotransferase. | ||
| Prosite: | PDOC00519; | ||
| PDB: |
|
||
| Cath: | 3.40.640.10; 3.90.1150.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.6.1.13 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.13 |
| KEGG Enzyme Link: | KEGG2.6.1.13 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.13 |
| ExPASy Enzyme Link: | ExPASy2.6.1.13 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.13 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.13 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.13 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.13 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.13 |
| RHEA:25160 | 2-oxoglutarate + L-ornithine = L-glutamate + L-glutamate 5-semialdehyde |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH2;+0:6]-[NH2;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:7].[*:5]-[CH;+0:6]=[O;H0;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mycobacterium tuberculosis Is a Natural Ornithine Aminotransferase (rocD) Mutant and Depends on Rv2323c for Growth on Arginine. | Hampel A, Huber C, Geffers R, Spona-Friedl M, Eisenreich W, Bange FC | 2015 | 26368558 |
| Biochemical characterization, homology modeling and docking studies of ornithine delta-aminotransferase--an important enzyme in proline biosynthesis of plants. | Sekhar PN, Amrutha RN, Sangam S, Verma DP, Kishor PB | 2007 Nov | 17604199 |
| RHEA:13877 | a 2-oxocarboxylate + L-ornithine = an L-alpha-amino acid + L-glutamate 5-semialdehyde |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH2;+0:6]-[NH2;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:7].[*:5]-[CH;+0:6]=[O;H0;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isolation of the ornithine-delta-aminotransferase cDNA and effect of salt stress on its expression in Arabidopsis thaliana. | Roosens NH, Thu TT, Iskandar HM, Jacobs M | 1998 May | 9576796 |
| An alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme. | Romagnoli G, Verhoeven MD, Mans R, Fleury Rey Y, Bel-Rhlid R, van den Broek M, Seifar RM, Ten Pierick A, Thompson M, Müller V, Wahl SA, Pronk JT, Daran JM | 2014 Jul | 24912400 |