EC number:2.6.1.2
| ID: | 2.6.1.2 |
|---|---|
| Description: | Alanine transaminase. |
| Alternative Name: |
Glutamic--pyruvic transaminase. Glutamic--alanine transaminase. Alanine aminotransferase. |
| Cath: | 1.10.287.1970; 3.40.640.10; 3.90.1150.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.6.1.2 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.2 |
| KEGG Enzyme Link: | KEGG2.6.1.2 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.2 |
| ExPASy Enzyme Link: | ExPASy2.6.1.2 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.2 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.2 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.2 |
| RHEA:19453 | 2-oxoglutarate + L-alanine = L-glutamate + pyruvate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver. | Jadhao SB, Yang RZ, Lin Q, Hu H, Anania FA, Shuldiner AR, Gong DW | 2004 May | 15122758 |
| cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. | Yang RZ, Blaileanu G, Hansen BC, Shuldiner AR, Gong DW | 2002 Mar | 11863375 |