EC number:2.6.1.52
| ID: | 2.6.1.52 | ||
|---|---|---|---|
| Description: | Phosphoserine transaminase. | ||
| Alternative Name: |
PSAT. Phosphoserine aminotransferase. Phosphohydroxypyruvic--glutamic transaminase. Phosphohydroxypyruvate transaminase. L-phosphoserine aminotransferase. Hydroxypyruvic phosphate--glutamic transaminase. 3PHP transaminase. 3-phosphoserine aminotransferase. | ||
| Prosite: | PDOC00514; | ||
| PDB: |
|
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| Cath: | 3.20.20.70; 3.30.360.10; 3.40.50.720; 3.40.50.880; 3.40.640.10; 3.90.1150.10; 2.30.110.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.6.1.52 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.52 |
| KEGG Enzyme Link: | KEGG2.6.1.52 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.52 |
| ExPASy Enzyme Link: | ExPASy2.6.1.52 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.52 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.52 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.52 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.52 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.52 |
| RHEA:16573 | 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 4-O-phosphoryl-L-threonine, a substrate of the pdxC(serC) gene product involved in vitamin B6 biosynthesis. | Drewke C, Klein M, Clade D, Arenz A, Müller R, Leistner E | 1996 Jul 22 | 8706854 |
| 4-Phospho-hydroxy-L-threonine is an obligatory intermediate in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12. | Zhao G, Winkler ME | 1996 Jan 15 | 8595869 |
| A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria. | Zhao G, Winkler ME | 1996 Jan | 8550422 |
| Studies on phosphoserine aminotransferase of sheep brain. | Hirsch H, Greenberg DM | 1967 May 10 | 6022873 |
| THE PATHWAY AND CONTROL OF SERINE BIOSYNTHESIS IN ESCHERICHIA COLI. | PIZER LI | 1963 Dec | 14086727 |
| RHEA:14329 | 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 4-O-phosphoryl-L-threonine, a substrate of the pdxC(serC) gene product involved in vitamin B6 biosynthesis. | Drewke C, Klein M, Clade D, Arenz A, Müller R, Leistner E | 1996 Jul 22 | 8706854 |
| 4-Phospho-hydroxy-L-threonine is an obligatory intermediate in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12. | Zhao G, Winkler ME | 1996 Jan 15 | 8595869 |
| Studies on phosphoserine aminotransferase of sheep brain. | Hirsch H, Greenberg DM | 1967 May 10 | 6022873 |
| A critical look at geriatrics in a teaching hospital: Part I. The situation. | Tibbit LR | 1979 Oct 13 | 550422 |
| THE PATHWAY AND CONTROL OF SERINE BIOSYNTHESIS IN ESCHERICHIA COLI. | PIZER LI | 1963 Dec | 14086727 |