EC number:2.6.1.57

Enzyme

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     2. Transferases
        2.6 Transferring nitrogenous groups
            2.6.1 Transaminases
ID:2.6.1.57
Description:Aromatic-amino-acid transaminase.
Prosite: PDOC00098;
PDB:
PDBScop
Cath: 1.10.20.110; 3.40.640.10; 3.90.1150.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.6.1.57
BRENDA Enzyme Link: BRENDA 2.6.1.57
KEGG Enzyme Link: KEGG2.6.1.57
BioCyc Enzyme Link: BioCyc 2.6.1.57
ExPASy Enzyme Link: ExPASy2.6.1.57
EC2PDB Enzyme Link: EC2PDB 2.6.1.57
ExplorEnz Enzyme Link: ExplorEnz 2.6.1.57
PRIAM enzyme-specific profiles Link: PRIAM 2.6.1.57
IntEnz Enzyme Link: IntEnz 2.6.1.57
MEDLINE Enzyme Link: MEDLINE 2.6.1.57

EC number:2.6.1.57

MSA:

2.6.1.57;
Phylogenetic Tree:

2.6.1.57;
Uniprot:
M-CSA:
RHEA:15093 2-oxoglutarate + L-tyrosine = 3-(4-hydroxyphenyl)pyruvate + L-glutamate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Tyrosine aminotransferase catalyzes the final step of methionine recycling in Klebsiella pneumoniae.Heilbronn J, Wilson J, Berger BJ1999 Mar10074065
RHEA:17533 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of aromatic aminotransferases from the hyperthermophilic archaeon Thermococcus litoralis.Andreotti G, Cubellis MV, Nitti G, Sannia G, Mai X, Marino G, Adams MW1994 Mar 18125113
Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli.Mavrides C, Orr W1975 Jun 10236311
In vitro characterization of enzymes involved in the synthesis of nonproteinogenic residue (2S,3S)-beta-methylphenylalanine in glycopeptide antibiotic mannopeptimycin.Huang YT, Lyu SY, Chuang PH, Hsu NS, Li YS, Chan HC, Huang CJ, Liu YC, Wu CJ, Yang WB, Li TL2009 Oct 1219731276
RHEA:25152 2-oxoglutarate + L-phenylalanine = 3-phenylpyruvate + L-glutamate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction
RHEA:25796 2-oxoglutarate + L-methionine = 4-(methylsulfanyl)-2-oxobutanoate + L-glutamate
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli.Mavrides C, Orr W1975 Jun 10236311