EC number:2.6.1.62
| ID: | 2.6.1.62 | ||
|---|---|---|---|
| Description: | Adenosylmethionine--8-amino-7-oxononanoate transaminase. | ||
| Alternative Name: |
DAPA aminotransferase. Adenosylmethionine--8-amino-7-oxononanoate aminotransferase. 7,8-diaminononanoate aminotransferase. 7,8-diamino-pelargonic acid aminotransferase. | ||
| Prosite: | PDOC00519; | ||
| PDB: |
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| Cath: | 3.40.640.10; 3.90.1150.10; 3.40.50.300; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.6.1.62 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.62 |
| KEGG Enzyme Link: | KEGG2.6.1.62 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.62 |
| ExPASy Enzyme Link: | ExPASy2.6.1.62 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.62 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.62 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.62 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.62 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.62 |
| RHEA:16861 | 8-amino-7-oxononanoate + S-adenosyl-L-methionine = 7,8-diaminononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. | Sandmark J, Eliot AC, Famm K, Schneider G, Kirsch JF | 2004 Feb 10 | 14756557 |
| The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation. | Eliot AC, Sandmark J, Schneider G, Kirsch JF | 2002 Oct 22 | 12379100 |
| Purification and properties of 7, 8-diaminopelargonic acid aminotransferase. | Stoner GL, Eisenberg MA | 1975 Jun 10 | 1092681 |
| Crystal structure of diaminopelargonic acid synthase: evolutionary relationships between pyridoxal-5'-phosphate-dependent enzymes. | Käck H, Sandmark J, Gibson K, Schneider G, Lindqvist Y | 1999 Aug 27 | 10452893 |