3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.6.1.85
BRENDA Enzyme Link: BRENDA 2.6.1.85
KEGG Enzyme Link: KEGG2.6.1.85
BioCyc Enzyme Link: BioCyc 2.6.1.85
ExPASy Enzyme Link: ExPASy2.6.1.85
EC2PDB Enzyme Link: EC2PDB 2.6.1.85
ExplorEnz Enzyme Link: ExplorEnz 2.6.1.85
PRIAM enzyme-specific profiles Link: PRIAM 2.6.1.85
IntEnz Enzyme Link: IntEnz 2.6.1.85
MEDLINE Enzyme Link: MEDLINE 2.6.1.85
MSA:

2.6.1.85;

Phylogenetic Tree:

2.6.1.85;

Uniprot:
M-CSA:
RHEA:11672 chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[NH2;+0:4].[*:5]-[CH;+0:6](-[*:7])-[OH;+0:8]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:8].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Kinetic characterization of 4-amino 4-deoxychorismate synthase from Escherichia coli.Viswanathan VK, Green JM, Nichols BP1995 Oct7592344
p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase.Ye QZ, Liu J, Walsh CT1990 Dec2251281
The synthesis of pABA: Coupling between the glutamine amidotransferase and aminodeoxychorismate synthase domains of the bifunctional aminodeoxychorismate synthase from Arabidopsis thaliana.Camara D, Richefeu-Contesto C, Gambonnet B, Dumas R, Rébeillé F2011 Jan 120851095
2-Amino-2-deoxyisochorismate is a key intermediate in Bacillus subtilis p-aminobenzoic acid biosynthesis.Schadt HS, Schadt S, Oldach F, Süssmuth RD2009 Mar 1819275258
Direct detection and kinetic analysis of covalent intermediate formation in the 4-amino-4-deoxychorismate synthase catalyzed reaction.He Z, Toney MD2006 Apr 1816605270
Folate synthesis in plants: purification, kinetic properties, and inhibition of aminodeoxychorismate synthase.Sahr T, Ravanel S, Basset G, Nichols BP, Hanson AD, Rébeillé F2006 May 1516466344
Folate synthesis in plants: the p-aminobenzoate branch is initiated by a bifunctional PabA-PabB protein that is targeted to plastids.Basset GJ, Quinlivan EP, Ravanel S, Rébeillé F, Nichols BP, Shinozaki K, Seki M, Adams-Phillips LC, Giovannoni JJ, Gregory JF 3rd, Hanson AD2004 Feb 1014745019