EC number:2.6.1.86
| ID: | 2.6.1.86 |
|---|---|
| Description: | 2-amino-4-deoxychorismate synthase. |
| Alternative Name: |
ADIC synthase. 2-amino-2-deoxyisochorismate synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.6.1.86 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.86 |
| KEGG Enzyme Link: | KEGG2.6.1.86 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.86 |
| ExPASy Enzyme Link: | ExPASy2.6.1.86 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.86 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.86 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.86 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.86 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.86 |
| RHEA:25512 | (2S)-2-amino-4-deoxychorismate + L-glutamate = chorismate + L-glutamine |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[CH;+0:4]=[CH;+0:5]-[*:6]-[CH;+0:7]-1-[NH2;+0:8].[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]>>[*:1]-[C;H0;+0:2]1=[CH;+0:7]-[*:6]-[CH;+0:5](-[OH;+0:12])-[CH;+0:4]=[CH;+0:3]-1.[*:9]=[C;H0;+0:10](-[*:11])-[NH2;+0:8] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism. | Van Lanen SG, Lin S, Shen B | 2008 Jan 15 | 18182490 |
| Phenazine natural products: biosynthesis, synthetic analogues, and biological activity. | Laursen JB, Nielsen J | 2004 Mar | 15008629 |
| Phenazine biosynthesis in Pseudomonas fluorescens: branchpoint from the primary shikimate biosynthetic pathway and role of phenazine-1,6-dicarboxylic acid. | McDonald M, Mavrodi DV, Thomashow LS, Floss HG | 2001 Sep 26 | 11562236 |