EC number:2.6.1.95
| ID: | 2.6.1.95 |
|---|---|
| Description: | Neomycin C transaminase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.6.1.95 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.95 |
| KEGG Enzyme Link: | KEGG2.6.1.95 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.95 |
| ExPASy Enzyme Link: | ExPASy2.6.1.95 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.95 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.95 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.95 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.95 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.95 |
| RHEA:33959 | 2-oxoglutarate + neomycin C = 6'''-deamino-6'''-oxoneomycin C + L-glutamate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH2;+0:6]-[NH2;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:7].[*:5]-[CH;+0:6]=[O;H0;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation. | Park JW, Park SR, Nepal KK, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ | 2011 Oct 9 | 21983602 |
| The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin. | Clausnitzer D, Piepersberg W, Wehmeier UF | 2011 Sep | 21689223 |
| Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin. | Huang F, Spiteller D, Koorbanally NA, Li Y, Llewellyn NM, Spencer JB | 2007 Feb 12 | 17206729 |