Enzyme

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     2. Transferases
        2.6 Transferring nitrogenous groups
            2.6.1 Transaminases
ID:2.6.1.96
Description:4-aminobutyrate--pyruvate transaminase.
Alternative Name: Gamma-aminobutyric acid pyruvate transaminase.
Gamma-aminobutyrate aminotransaminase.
GABA transaminase.
4-aminobutyrate aminotransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.6.1.96
BRENDA Enzyme Link: BRENDA 2.6.1.96
KEGG Enzyme Link: KEGG2.6.1.96
BioCyc Enzyme Link: BioCyc 2.6.1.96
ExPASy Enzyme Link: ExPASy2.6.1.96
EC2PDB Enzyme Link: EC2PDB 2.6.1.96
ExplorEnz Enzyme Link: ExplorEnz 2.6.1.96
PRIAM enzyme-specific profiles Link: PRIAM 2.6.1.96
IntEnz Enzyme Link: IntEnz 2.6.1.96
MEDLINE Enzyme Link: MEDLINE 2.6.1.96
MSA:

2.6.1.96;

Phylogenetic Tree:

2.6.1.96;

Uniprot:
M-CSA:
RHEA:32267 4-aminobutanoate + glyoxylate = glycine + succinate semialdehyde
RULE(radius=1) [*:1]-[CH2;+0:2]-[NH2;+0:3].[*:4]-[CH;+0:5]=[O;H0;+0:6]>>[*:4]-[CH2;+0:5]-[NH2;+0:3].[*:1]-[CH;+0:2]=[O;H0;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate.Clark SM, Di Leo R, Van Cauwenberghe OR, Mullen RT, Shelp BJ200919470656
Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate.Clark SM, Di Leo R, Dhanoa PK, Van Cauwenberghe OR, Mullen RT, Shelp BJ200919264755

RHEA:32263 4-aminobutanoate + pyruvate = L-alanine + succinate semialdehyde
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH2;+0:6]-[NH2;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:7].[*:5]-[CH;+0:6]=[O;H0;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate.Clark SM, Di Leo R, Van Cauwenberghe OR, Mullen RT, Shelp BJ200919470656
Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate.Clark SM, Di Leo R, Dhanoa PK, Van Cauwenberghe OR, Mullen RT, Shelp BJ200919264755
Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels.Palanivelu R, Brass L, Edlund AF, Preuss D2003 Jul 1112859897