Enzyme

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     2. Transferases
        2.6 Transferring nitrogenous groups
            2.6.1 Transaminases
ID:2.6.1.99
Description:L-tryptophan--pyruvate aminotransferase.
Cath: 3.40.640.10; 3.90.1150.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.6.1.99
BRENDA Enzyme Link: BRENDA 2.6.1.99
KEGG Enzyme Link: KEGG2.6.1.99
BioCyc Enzyme Link: BioCyc 2.6.1.99
ExPASy Enzyme Link: ExPASy2.6.1.99
EC2PDB Enzyme Link: EC2PDB 2.6.1.99
ExplorEnz Enzyme Link: ExplorEnz 2.6.1.99
PRIAM enzyme-specific profiles Link: PRIAM 2.6.1.99
IntEnz Enzyme Link: IntEnz 2.6.1.99
MEDLINE Enzyme Link: MEDLINE 2.6.1.99
MSA:

2.6.1.99;

Phylogenetic Tree:

2.6.1.99;

Uniprot:
M-CSA:
RHEA:27586 L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The main auxin biosynthesis pathway in Arabidopsis.Mashiguchi K, Tanaka K, Sakai T, Sugawara S, Kawaide H, Natsume M, Hanada A, Yaeno T, Shirasu K, Yao H, McSteen P, Zhao Y, Hayashi K, Kamiya Y, Kasahara H2011 Nov 822025724
Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants.Zhao Y2012 Mar22155950
vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize.Phillips KA, Skirpan AL, Liu X, Christensen A, Slewinski TL, Hudson C, Barazesh S, Cohen JD, Malcomber S, McSteen P2011 Feb21335375
Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants.Tao Y, Ferrer JL, Ljung K, Pojer F, Hong F, Long JA, Li L, Moreno JE, Bowman ME, Ivans LJ, Cheng Y, Lim J, Zhao Y, Ballaré CL, Sandberg G, Noel JP, Chory J2008 Apr 418394996